Multipath Curved Planar Reformations of Peripheral CT Angiography: Diagnostic Accuracy and Time Efficiency

Markus Schreiner, Hannes Platzgummer, Sylvia Unterhumer, Michael Weber, Gabriel Mistelbauer, Meister Eduard Gröller, Christian Loewe, Rüdiger Schernthaner
Multipath Curved Planar Reformations of Peripheral CT Angiography: Diagnostic Accuracy and Time Efficiency
CardioVascular and Interventional Radiology, 41(5):718-725, May 2018.

Information

  • Publication Type: Journal Paper (without talk)
  • Workgroup(s)/Project(s):
  • Date: May 2018
  • DOI: 10.1007/s00270-017-1846-3
  • ISSN: 0174-1551
  • Journal: CardioVascular and Interventional Radiology
  • Number: 5
  • Pages (from): 718
  • Pages (to): 725
  • Volume: 41
  • Keywords: PAD, CTA, 3D reformation, mpCPRs

Abstract

Objectives To compare diagnostic performance and time efficiency between 3D multipath curved planar reformations (mpCPRs) and axial images of CT angiography for the pre-interventional assessment of peripheral arterial disease (PAD), with digital subtraction angiography as the standard of reference. Methods Forty patients (10 females, mean age 72 years), referred to CTA prior to endovascular treatment of PAD, were prospectively included and underwent peripheral CT angiography. A semiautomated toolbox was used to render mpCPRs. Twenty-one arterial segments were defined in each leg; for each segment, the presence of stenosis[70% was assessed on mpCPRs and axial images by two readers, independently, with digital subtraction angiography as gold standard. Results Both readers reached lower sensitivity (Reader 1: 91 vs. 94%, p = 0.08; Reader 2: 89 vs. 93%, p = 0.03) but significantly higher specificity (Reader 1: 94 vs. 89%, p\0.01; Reader 2: 96 vs. 95%, p = 0.01) with mpCPRs than with axial images. Reader 1 achieved significantly higher accuracy with mpCPRs (93 vs. 91%, p = 0.02), and Reader 2 had similar overall accuracy in both evaluations (94 vs. 94%, p = 0.96). Both readers read mpCPRs significantly faster than axial images (Reader 1: 504500 based on mpCPRs vs. 704000 based on axial images; Reader 2: 404100 based on mpCPRs vs. 605700 based on axial images; p\0.01). Conclusions mpCPRs are a promising 3D reformation technique that facilitates a fast assessment of PAD with high diagnostic accuracy.

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BibTeX

@article{Schernthaner-2017-MCP,
  title =      "Multipath Curved Planar Reformations of Peripheral CT
               Angiography: Diagnostic Accuracy and Time Efficiency",
  author =     "Markus Schreiner and Hannes Platzgummer and Sylvia
               Unterhumer and Michael Weber and Gabriel Mistelbauer and
               Meister Eduard Gr\"{o}ller and Christian Loewe and
               R\"{u}diger Schernthaner",
  year =       "2018",
  abstract =   "Objectives To compare diagnostic performance and time
               efficiency between 3D multipath curved planar reformations
               (mpCPRs) and axial images of CT angiography for the
               pre-interventional assessment of peripheral arterial disease
               (PAD), with digital subtraction angiography as the standard
               of reference. Methods Forty patients (10 females, mean age
               72 years), referred to CTA prior to endovascular treatment
               of PAD, were prospectively included and underwent peripheral
               CT angiography. A semiautomated toolbox was used to render
               mpCPRs. Twenty-one arterial segments were defined in each
               leg; for each segment, the presence of stenosis[70% was
               assessed on mpCPRs and axial images by two readers,
               independently, with digital subtraction angiography as gold
               standard. Results Both readers reached lower sensitivity
               (Reader 1: 91 vs. 94%, p = 0.08; Reader 2: 89 vs. 93%, p =
               0.03) but significantly higher specificity (Reader 1: 94 vs.
               89%, p\0.01; Reader 2: 96 vs. 95%, p = 0.01) with mpCPRs
               than with axial images. Reader 1 achieved significantly
               higher accuracy with mpCPRs (93 vs. 91%, p = 0.02), and
               Reader 2 had similar overall accuracy in both evaluations
               (94 vs. 94%, p = 0.96). Both readers read mpCPRs
               significantly faster than axial images (Reader 1: 504500
               based on mpCPRs vs. 704000 based on axial images; Reader 2:
               404100 based on mpCPRs vs. 605700 based on axial images;
               p\0.01). Conclusions mpCPRs are a promising 3D reformation
               technique that facilitates a fast assessment of PAD with
               high diagnostic accuracy.",
  month =      may,
  doi =        "10.1007/s00270-017-1846-3",
  issn =       "0174-1551",
  journal =    "CardioVascular and Interventional Radiology",
  number =     "5",
  volume =     "41",
  pages =      "718--725",
  keywords =   "PAD, CTA, 3D reformation, mpCPRs",
  URL =        "/research/publications/2018/Schernthaner-2017-MCP/",
}