Illustrating Polymerization using Three-level Model Fusion

Ivan Kolesár, Julius Parulek, Ivan Viola, Stefan Bruckner, Anne-Kristin Stavrum, Helwig Hauser
Illustrating Polymerization using Three-level Model Fusion
In Proceedings of IEEE BioVis 2014, pages 1-22. July 2014.

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Abstract

Research in cell biology is steadily contributing new knowledge about many di?erent aspects of physiological processes like polymerization, both with respect to the involved molecular structures as well as their related function. Illustrations of the spatio-temporal development of such processes are not only used in biomedical education, but also can serve scientists as an additional platform for in-silico experiments. In this paper, we contribute a new, three-level modeling approach to illustrate physiological processes from the class of polymerization at di?erent time scales. We integrate physical and empirical modeling, according to which approach suits the di?erent involved levels of detail best, and we additionally enable a simple form of interactive steering while the process is illustrated. We demonstrate the suitability of our approach in the context of several polymerization processes and report from a ?rst evaluation with domain experts.

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BibTeX

@inproceedings{kolesar-ivan-2014-polymers,
  title =      "Illustrating Polymerization using Three-level Model Fusion",
  author =     "Ivan Koles\'{a}r and Julius Parulek and Ivan Viola and
               Stefan Bruckner and Anne-Kristin Stavrum and Helwig Hauser",
  year =       "2014",
  abstract =   "Research in cell biology is steadily contributing new
               knowledge about many di?erent aspects of physiological
               processes like polymerization, both with respect to the
               involved molecular structures as well as their related
               function. Illustrations of the spatio-temporal development
               of such processes are not only used in biomedical education,
               but also can serve scientists as an additional platform for
               in-silico experiments. In this paper, we contribute a new,
               three-level modeling approach to illustrate physiological
               processes from the class of polymerization at di?erent time
               scales. We integrate physical and empirical modeling,
               according to which approach suits the di?erent involved
               levels of detail best, and we additionally enable a simple
               form of interactive steering while the process is
               illustrated. We demonstrate the suitability of our approach
               in the context of several polymerization processes and
               report from a ?rst evaluation with domain experts.",
  month =      jul,
  booktitle =  "Proceedings of IEEE BioVis 2014",
  location =   "Boston, USA",
  organization = "4th Symposium on Biological Data Visualization (in
               Conjunction with the International Conference on Intelligent
               Systems for Molecular Biology (ISMB 2014)) ",
  publisher =  "IEEE Digital Library",
  pages =      "1--22",
  URL =        "https://www.cg.tuwien.ac.at/research/publications/2014/kolesar-ivan-2014-polymers/",
}